clusterProfiler模式物种的GO与KEGG功能富集与注释

支持的20个模式物种列表如下：

| Package | Maintainer | Title | Index |
| org.Hs.eg.db | Bioconductor Package Maintainer | Genome wide annotation for Human | 3 |
| org.Mm.eg.db | Bioconductor Package Maintainer | Genome wide annotation for Mouse | 5 |
| org.Rn.eg.db | Bioconductor Package Maintainer | Genome wide annotation for Rat | 19 |
| org.Sc.sgd.db | Bioconductor Package Maintainer | Genome wide annotation for Yeast | 28 |
| org.Dm.eg.db | Bioconductor Package Maintainer | Genome wide annotation for Fly | 31 |
| org.At.tair.db | Bioconductor Package Maintainer | Genome wide annotation for Arabidopsis | 32 |
| org.Dr.eg.db | Bioconductor Package Maintainer | Genome wide annotation for Zebrafish | 37 |
| org.Ce.eg.db | Bioconductor Package Maintainer | Genome wide annotation for Worm | 44 |
| org.Bt.eg.db | Bioconductor Package Maintainer | Genome wide annotation for Bovine | 53 |
| org.Gg.eg.db | Bioconductor Package Maintainer | Genome wide annotation for Chicken | 56 |
| org.Cf.eg.db | Bioconductor Package Maintainer | Genome wide annotation for Canine | 61 |
| org.Ss.eg.db | Bioconductor Package Maintainer | Genome wide annotation for Pig | 64 |
| org.Mmu.eg.db | Bioconductor Package Maintainer | Genome wide annotation for Rhesus | 70 |
| org.EcK12.eg.db | Bioconductor Package Maintainer | Genome wide annotation for E coli strain K12 | 76 |
| org.Xl.eg.db | Bioconductor Package Maintainer | Genome wide annotation for Xenopus | 111 |
| org.Ag.eg.db | Bioconductor Package Maintainer | Genome wide annotation for Anopheles | 114 |
| org.Pt.eg.db | Bioconductor Package Maintainer | Genome wide annotation for Chimp | 121 |
| org.Pf.plasmo.db | Bioconductor Package Maintainer | Genome wide annotation for Malaria | 132 |
| org.EcSakai.eg.db | Bioconductor Package Maintainer | Genome wide annotation for E coli strain Sakai | 137 |
| org.Mxanthus.db | Eduardo Illueca Fernández | Genome wide annotation for Myxococcus xanthus DK 1622 | 944 |

简单总结clusterProfiler包进行GO、KEGG的富集分析方法，结果输出及内置的图形展示。

安装富集分析需要的包

if (!requireNamespace("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("enrichplot")
BiocManager::install("GSEABase")
BiocManager::install("pathview")
BiocManager::install("clusterProfiler")

20个模式物种注释文件：https://www.omicsclass.com/article/1244

BiocManager::install("org.Hs.eg.db")

非模式物种需要的包

BiocManager::install("AnnotationHub")
BiocManager::install("biomaRt")

#######加载必要的包#####################################################
library(clusterProfiler)
library(pathview)
library(GSEABase)
library(enrichplot)

模式物种

library(AnnotationHub)
library(biomaRt)
############################################################