同ubuntu下配置：（转自：http://archive.cnblogs.com/a/2214282/）
Master 1 Config File:
#
# The MySQL database server configuration file.
#
[client]
port = 3306
socket = /var/run/mysqld/mysqld.sock
default-character-set = utf8
# This was formally known as [safe_mysqld]. Both versions are currently parsed.
[mysqld_safe]
socket = /var/run/mysqld/mysqld.sock
nice = 0
[mysqld]
#My Features
default-character-set = utf8
skip-name-resolve
default-storage-engine = InnoDB
default-table-type = InnoDB
innodb_flush_log_at_trx_commit=0
federated
#Master
server-id = 1
log-bin=mysql-bin
binlog-do-db=s3
binlog-ignore-db=mysql
sync_binlog=1
auto_increment_increment=2
auto_increment_offset=1
#Slave
skip-name-resolve
slave-skip-errors
log-slave-updates
master-user=sync
master-password=123456
master-port=3306
master-connect-retry=30
replicate-do-db=s3
relay-log=S3-DB-M-1-relay-bin
#
# * Basic Settings
#
user = mysql
socket = /var/run/mysqld/mysqld.sock
port = 3306
basedir = /usr
datadir = /var/lib/mysql
tmpdir = /tmp
skip-external-locking
#
# Instead of skip-networking the default is now to listen only on
# localhost which is more compatible and is not less secure.
#bind-address = 127.0.0.1
#
# * Fine Tuning
#
key_buffer = 16M
max_allowed_packet = 16M
thread_stack = 192K
thread_cache_size = 8
# This replaces the startup script and checks MyISAM tables if needed
# the first time they are touched
myisam-recover = BACKUP
#max_connections = 100
#table_cache = 64
#thread_concurrency = 10
#
# * Query Cache Configuration
#
query_cache_limit = 1M
query_cache_size = 16M
#
# * Logging and Replication
#
# Both location gets rotated by the cronjob.
# Be aware that this log type is a performance killer.
# As of 5.1 you can enable the log at runtime!
#general_log_file = /var/log/mysql/mysql.log
#general_log = 1
log_error = /var/log/mysql/error.log
# Here you can see queries with especially long duration
#log_slow_queries = /var/log/mysql/mysql-slow.log
#long_query_time = 2
#log-queries-not-using-indexes
#
# The following can be used as easy to replay backup logs or for replication.
# note: if you are setting up a replication slave, see README.Debian about
# other settings you may need to change.
#server-id = 1
#log_bin = /var/log/mysql/mysql-bin.log
expire_logs_days = 10
max_binlog_size = 100M
#binlog_do_db = include_database_name
#binlog_ignore_db = include_database_name
[mysqldump]
quick
quote-names
max_allowed_packet = 24M
[mysql]
#no-auto-rehash # faster start of mysql but no tab completition
[isamchk]
key_buffer = 16M
#
# * IMPORTANT: Additional settings that can override those from this file!
# The files must end with '.cnf', otherwise they'll be ignored.
#
!includedir /etc/mysql/conf.d/
Master 2 Config File:
#
# The MySQL database server configuration file.
#
# You can copy this to one of:
# - "/etc/mysql/my.cnf" to set global options,
# - "~/.my.cnf" to set user-specific options.
#
# One can use all long options that the program supports.
# Run program with --help to get a list of available options and with
# --print-defaults to see which it would actually understand and use.
#
# For explanations see
# http://dev.mysql.com/doc/mysql/en/server-system-variables.html
# This will be passed to all mysql clients
# It has been reported that passwords should be enclosed with ticks/quotes
# escpecially if they contain "#" chars...
# Remember to edit /etc/mysql/debian.cnf when changing the socket location.
[client]
port = 3306
socket = /var/run/mysqld/mysqld.sock
default-character-set = utf8
# Here is entries for some specific programs
# The following values assume you have at least 32M ram
# This was formally known as [safe_mysqld]. Both versions are currently parsed.
[mysqld_safe]
socket = /var/run/mysqld/mysqld.sock
nice = 0
[mysqld]
default-character-set = utf8
skip-name-resolve
default-storage-engine = InnoDB
default-table-type = InnoDB
innodb_flush_log_at_trx_commit=0
federated
#master
server-id = 2
log-bin=mysql-bin
binlog-do-db=s3
binlog-ignore-db=mysql
sync_binlog=1
auto_increment_increment=2
auto_increment_offset=2
#Slave
skip-name-resolve
slave-skip-errors
log-slave-updates
master-user=sync
master-password=123456
master-port=3306
master-connect-retry=30 #断网后间隔30秒重连
replicate-do-db=s3
relay-log=S3-DB-M-2-relay-bin
#
# * Basic Settings
#
#
# * IMPORTANT
# If you make changes to these settings and your system uses apparmor, you may
# also need to also adjust /etc/apparmor.d/usr.sbin.mysqld.
#
user = mysql
socket = /var/run/mysqld/mysqld.sock
port = 3306
basedir = /usr
datadir = /var/lib/mysql
tmpdir = /tmp
skip-external-locking
#
# Instead of skip-networking the default is now to listen only on
# localhost which is more compatible and is not less secure.
#bind-address = 127.0.0.1
#
# * Fine Tuning
#
key_buffer = 16M
max_allowed_packet = 16M
thread_stack = 192K
thread_cache_size = 8
# This replaces the startup script and checks MyISAM tables if needed
# the first time they are touched
myisam-recover = BACKUP
#max_connections = 100
#table_cache = 64
#thread_concurrency = 10
#
# * Query Cache Configuration
#
query_cache_limit = 1M
query_cache_size = 16M
#
# * Logging and Replication
#
# Both location gets rotated by the cronjob.
# Be aware that this log type is a performance killer.
# As of 5.1 you can enable the log at runtime!
#general_log_file = /var/log/mysql/mysql.log
#general_log = 1
log_error = /var/log/mysql/error.log
# Here you can see queries with especially long duration
#log_slow_queries = /var/log/mysql/mysql-slow.log
#long_query_time = 2
#log-queries-not-using-indexes
#
# The following can be used as easy to replay backup logs or for replication.
# note: if you are setting up a replication slave, see README.Debian about
# other settings you may need to change.
#server-id = 1
#log_bin = /var/log/mysql/mysql-bin.log
expire_logs_days = 10
max_binlog_size = 100M
#binlog_do_db = include_database_name
#binlog_ignore_db = include_database_name
#
# * InnoDB
#
# InnoDB is enabled by default with a 10MB datafile in /var/lib/mysql/.
# Read the manual for more InnoDB related options. There are many!
#
# * Security Features
#
# Read the manual, too, if you want chroot!
# chroot = /var/lib/mysql/
#
# For generating SSL certificates I recommend the OpenSSL GUI "tinyca".
#
# ssl-ca=/etc/mysql/cacert.pem
# ssl-cert=/etc/mysql/server-cert.pem
# ssl-key=/etc/mysql/server-key.pem
[mysqldump]
quick
quote-names
max_allowed_packet = 24M
[mysql]
#no-auto-rehash # faster start of mysql but no tab completition
[isamchk]
key_buffer = 16M
#
# * IMPORTANT: Additional settings that can override those from this file!
# The files must end with '.cnf', otherwise they'll be ignored.
#
!includedir /etc/mysql/conf.d/
Centos
转自：http://whxhz.iteye.com/blog/1164662
不同os下，其实配置也一样，先单向建立master-slave，再逆向建立master-slave即可。