"目录号: HY-14471
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Cetilistat是胰腺癌和胃肠道脂酶的抑制剂。它有糖尿病和非糖尿病的肥胖治疗中有很大的作用。
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SBE-β-CD-MPTP hydrochloride-Cyclosporin A-Etomoxir-Auranofin-GKT137831-Ceruletide-Acetylcysteine-JC-1-BPTES-Brassinolide-FCCP-IPTG-MTT-RSL3 1S,3R--
生物活性
Description
Cetilistat is an inhibitor of pancreatic and gastrointestinal lipases. It has great treatment of obesity in both diabetic and non-diabetic patients.
Clinical Trial
NCT00148382
Alizyme
Obesity
April 2005
Phase 1
NCT00156897
Alizyme
Non-Insulin-Dependent Diabetes Mellitus-Obesity
December 2004
Phase 2
NCT00148382
Alizyme
Obesity
April 2005
Phase 1
NCT00156897
Alizyme
Non-Insulin-Dependent Diabetes Mellitus-Obesity
December 2004
Phase 2
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References
[1].Andrew Bryson, Stephan de la Motte,et al. Reduction of dietary fat absorption by the novel gastrointestinal lipase inhibitor cetilistat in healthy volunteers.Br J Clin Pharmacol. 2009 Mar; 67(3): 309–315.
[2].Melvin George, Muthukumar Rajaram,et al. New and Emerging Drug Molecules Against Obesity.J CARDIOVASC PHARMACOL THER January 2014 vol. 19 no. 1 65-76
[3].Rebeca Carter, Angelina Mouralidarane,et al. Recent advancements in drug treatment of obesity.Clin Med October 1, 2012 vol. 12 no. 5 456-460