安装：
conda install orthomcl
复制orthomcl.config.template到工作目录下，改名为orthomcl.config
修改orthomcl.config的内容如下：
# this config assumes a mysql database named 'orthomcl'. adjust according
# to your situation.
dbVendor=mysql
dbConnectString=dbi:mysql:orthomcl:mysql_local_infile=1
dbLogin=Your_username
dbPassword=Your_password
similarSequencesTable=SimilarSequences
orthologTable=Ortholog
inParalogTable=InParalog
coOrthologTable=CoOrtholog
interTaxonMatchView=InterTaxonMatch
percentMatchCutoff=50
evalueExponentCutoff=-5
oracleIndexTblSpc=NONE
创建账户并运行
为了避免其它问题，用root账户登入mysql并把下面的命令运行一遍就行了。
mysql -uroot -ppasswd
CREATE USER 'jiayuxin'@'localhost' IDENTIFIED BY '111111'; #创建账户
grant all privileges on orthomcl.* to 'jiayuxin'@'localhost'; #把database orthomcl的权限授权给账户
ALTER USER 'jiayuxin'@'localhost' IDENTIFIED WITH mysql_native_password BY '111111'; #更改加密方法
也可以直接用自己的账户创建一个database，就不用root用户给授权了，以下是常用命令。
mysql -ujiayuxin -p111111
drop database orthomcl; #删除名为orthomcl的database
create database orthomcl; #创建一个名为orthomcl的database
show databases; #查看账户下存在的databases
使用root账户登录mysql
mysql -u root -p
输入密码进去mysql，使用SHOW VARIABLES LIKE 'local_infile';查看当前local_infile状态为OFF。
mysql> SHOW VARIABLES LIKE 'local_infile';
+---------------+-------+
| Variable_name | Value |
+---------------+-------+
| local_infile | OFF |
+---------------+-------+
1 row in set (0.00 sec)
使用SET GLOBAL local_infile = 1;修改local_infile格式，重新用SHOW VARIABLES LIKE 'local_infile';查看：
mysql> SHOW VARIABLES LIKE 'local_infile';
+---------------+-------+
| Variable_name | Value |
+---------------+-------+
| local_infile | ON |
+---------------+-------+
1 row in set (0.01 sec)
可以了。
运行到orthomclPairs时，出现错误提示DBD::mysql::st execute failed: The total number of locks exceeds the lock table size，查到两种办法，一种修改tmp变量的大小，另一种修改innodb_buffer_pool_size，都试一下。
进入mysql，输入show variables like "%tmp%";查看tmp大小：
mysql> show variables like "%tmp%";
+---------------------------------+-----------+
| Variable_name | Value |
+---------------------------------+-----------+
| default_tmp_storage_engine | InnoDB |
| innodb_tmpdir | |
| internal_tmp_mem_storage_engine | TempTable |
| slave_load_tmpdir | /tmp |
| tmp_table_size | 16777216 |
| tmpdir | /tmp |
+---------------------------------+-----------+
6 rows in set (0.02 sec)
修改为1G：
SET GLOBAL tmp_table_size =1024*1024*1024;
改完之后好像没变化，先不管，接着查看innodb_buffer_pool_size：
mysql> show variables like "%_buffer%";
+-------------------------------------+----------------+
| Variable_name | Value |
+-------------------------------------+----------------+
| bulk_insert_buffer_size | 8388608 |
| innodb_buffer_pool_chunk_size | 134217728 |
| innodb_buffer_pool_dump_at_shutdown | ON |
| innodb_buffer_pool_dump_now | OFF |
| innodb_buffer_pool_dump_pct | 25 |
| innodb_buffer_pool_filename | ib_buffer_pool |
| innodb_buffer_pool_in_core_file | ON |
| innodb_buffer_pool_instances | 1 |
| innodb_buffer_pool_load_abort | OFF |
| innodb_buffer_pool_load_at_startup | ON |
| innodb_buffer_pool_load_now | OFF |
| innodb_buffer_pool_size | 134217728 |
| innodb_change_buffer_max_size | 25 |
| innodb_change_buffering | all |
| innodb_log_buffer_size | 16777216 |
| innodb_sort_buffer_size | 1048576 |
| join_buffer_size | 262144 |
| key_buffer_size | 8388608 |
| myisam_sort_buffer_size | 8388608 |
| net_buffer_length | 16384 |
| preload_buffer_size | 32768 |
| read_buffer_size | 131072 |
| read_rnd_buffer_size | 262144 |
| sort_buffer_size | 262144 |
| sql_buffer_result | OFF |
+-------------------------------------+----------------+
25 rows in set (0.00 sec)
改为3G：
mysql> SET GLOBAL innodb_buffer_pool_size=3*1024*1024*1024;
Query OK, 0 rows affected (0.00 sec)
重新运行试试。
提示错误DBD::mysql::st execute failed: The table 'InplgOrthoInplg' is full at /Some_path/，查了下原因可能有两种：1.存放mysql数据的硬盘满了。2.参数设置太小了。
第一种情况，尝试更改mysql数据存放位置，始终报错，暂时放在原处，还够用。
第二种情况，在/etc/my.cnf文件中[mysqld]字段下面添加命令innodb_data_file_path=ibdata1:10G:autoextend，重新运行试试。