"目录号: HY-14645B
NF-κB-
DHMEQ racemate 是 DHMEQ 的外消旋体。(-)-DHMEQ 为 DHMEQ 的优性异构体，为 NF-kB 的有效抑制剂；(+)-DHMEQ 为 DHMEQ 的低活性光学异构体。
NF-κB
相关产品
BAY 11-7082-JSH-23-Pyrrolidinedithiocarbamate ammonium-Parthenolide-(-)-DHMEQ-Ginsenoside C-K-QNZ-Dihydroartemisinin-Sulfasalazine-Andrographolide-RTA-408-Tomatidine-BAY 11-7085-Baicalin-Ginsenoside Rb1-
生物活性
Description
DHMEQ racemate is the racemate of DHMEQ. (-)-DHMEQ, the eutomer of DHMEQ, is a newly developed NF-kB inhibitor, and (+)-DHMEQ is the distomer of DHMEQ.
References
[1].Kobayashi R, et al. A chemo-enzymatic expeditious route to racemic dihexanoyl (2R*,3R*,4R*)-dehydroxymethylepoxyquinomycin (DHMEQ), the precursor for lipase-catalyzed synthesis of the potent nuclear factor-κB inhibitor, (2S,3S,4S)-DHMEQ.
[2].Ohno O, et al. Inhibition of cellular adhesion in human umbilical vein endothelial cells by NF-kappaB inhibitor DHMEQ under flow. Oncol Res. 2005;15(4):189-97.