"目录号: HY-13718
Protein Tyrosine Kinase/RTK-
Oglufanide能够抑制VEGF,也能够抑制血管生成。
VEGFR
相关产品
Sorafenib-BIBF 1120-SU5416-Regorafenib-Ponatinib-Sunitinib-Cabozantinib-Vandetanib-Lenvatinib-Apatinib-Pazopanib-SU 5402-Foretinib-Axitinib-E-3810-
生物活性
Description
Oglufanide inhibits vascular endothelial growth factor (VEGF), which may inhibit angiogenesis.This agent has also been reported to stimulate the immune response to hepatitic C virus and intracellular bacterial infections.
Clinical Trial
NCT00003773
University of Southern California-National Cancer Institute (NCI)
Ovarian Cancer
February 1999
Phase 1
NCT00006037
University of Southern California-National Cancer Institute (NCI)
Colorectal Cancer
November 1999
Phase 2
NCT00017303
Cytran-National Cancer Institute (NCI)
Ovarian Cancer-Primary Peritoneal Cavity Cancer
January 2001
Phase 2
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References
[1].National Center for Biotechnology Information.