Week 7-8 L13-16

http://mooc.guokr.com/note/17440/

13.1Introduction to DNA Damage

13.2DNA Damage and Incorporation Errors

13.3DNA Damage Blocking Replication

13.4Consequences of DNA Damage and the Ames Test

14.1Examples of Direct DNA Repair

14.2Base Excision Repair

14.3Base Excision Repair of rNMPs

14.4Nucleotide Excision Repair in E. coli

14.5Transcription-Coupled Repair

14.6Trans lesion Synthesis

15.1Introduction

DNA双链断裂及修复方式

15.2Introduction to Double-Stranded Breaks

15.3Double-Stranded Breaks

15.4Introduction to Classical NHEJ1非同源性末端连接的经典途径

15.5Alternative NHEJ

15.6NHEJ Versus Recombinational重组 DSBR

16.1DNA Used in HR

重组修复DNA损伤

107、16.2The Steps of Homologous Recombination DSBR108、16.3Resolution of a Double Holliday Junction109、16.4Proteins of Homologous Recombination - RecBCD110、16.5RecBCD Mechanism111、16.6 RecBCD Structures112、16.7Proteins of Homologous Recombination - RecA113、16.8Strand Invasion and Assay114、16.9RecA Molecular Mechanism115、16.10Proteins of Homologous Recombination - RuvAB116、16.11Proteins of Homologous Recombin