代码
# encoding=utf-8
import os, time, re
import urllib.request
import urllib.parse
import ssl
ssl._create_default_https_context = ssl._create_unverified_context
retmax = 500
FAILURE = 0
SUCCESS = 1
startNum = 1
BASE = 'NARA'
FILES= ['Losartan','Valsartan','Irbesartan','Eprosartan','Candesartan','Telmisartan','Olmesartan']
# BASE = 'Triptans'
# FILES = ['Sumatriptan','Zolmitriptan',
# 'Naratriptan','Rizatriptan','Almotriptan',
# 'Frovatriptan','Eletriptan']
if not os.path.exists(BASE):
os.mkdir(BASE)
def lastline(fd):
lastNum = 0
print(fd)
if not os.path.isfile(fd):
f_check = open(fd, 'w')
f_check.close()
f = open(fd, 'r')
lines = f.readlines()
f.close()
if lines:
lastNum = int(lines[-1].strip())
return lastNum
def Download(drug, sleep_time, query_key, webenv, endNum):
lastNum = lastline('{}/{}/checkpoint.txt'.format(BASE,drug))
if lastNum == 0:
start = startNum - 1
else:
start = lastNum + retmax
# print(lastNum)
f_append = open('{}/{}/checkpoint.txt'.format(BASE, drug), 'a')
f_error = open('{}/{}/error.txt'.format(BASE, drug), 'a')
try:
for retstart in range(start, endNum, retmax):
time.sleep(sleep_time)
print('\tdownloading: %d - %d' % (retstart + 1, retstart + retmax))
urllib.request.urlretrieve('https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?'
'db=pubmed&query_key=%s&WebEnv=%s&retstart=%s&retmax=%s&retmode=xml' % (
query_key, webenv, retstart, retmax),
'%s/%s/%d-%d.xml' % (BASE, drug, retstart + 1, retstart + retmax))
f_append.write('%d\n' % (retstart))
f_append.flush()
except Exception as ex:
print(ex)
# print('\t\tbad connection!')
raise Exception()
return FAILURE
finally:
f_append.close()
f_error.close()
print('Downloading is done........................')
return SUCCESS
def Download_auto(fun, drug, query_key, webenv, endNum, sleep_time=5):
while True:
try:
value = fun(drug, sleep_time, query_key, webenv, endNum)
if value == SUCCESS:
break
except Exception as e:
sleep_time += 5
print('prolong sleep time:', sleep_time)
def main(drug):
"""主函数"""
if not os.path.exists('{}/{}'.format(BASE,drug)):
os.mkdir('{}/{}'.format(BASE,drug))
query = '%s[TIAB]+OR+%s[MH]' % (drug, drug)
url = 'https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term={}&usehistory=y'.format(query)
history = urllib.request.urlopen(url)
content = history.read().decode()
pattern = re.compile('(\d+) .*(\d+) .*(\S+) ')
s = pattern.search(content)
count = s.group(1)
query_key = s.group(2)
webenv = s.group(3)
print('total counts: %s' % count)
endNum = int(count)
print(endNum)
Download_auto(Download,drug, query_key, webenv, endNum)
if __name__ == '__main__':
start = time.time()
list(map(main, FILES))
print(time.time() - start)