细胞通讯iTALK使用 - 获取pathway LR信息

• 使用方法参考大佬写的就行 https://www.jianshu.com/p/dfe35a2a02d4

• 作者总结了一些pathway的LR pair，我们可以直接拿来使用。
  LR_database

加载进去是这样的

image.png

几个pathway的LR数量如下

image.png

可以使用这些分类信息进行文章crosstalk bubble plot的展示，比如这篇文章

image.png

The ligand-receptor pairs in CellChat retrieved from previous studies were divided into four groups including, cytokine/chemokine, immune checkpoint, growth factor, and others [37]. The crosstalk between cell analyses conducted via “CellChat” was as follows: (1) “createCellChat” function was applied to create “CellChat” object; (2) the “computeCommunProb,” “computeCommunProbPathway,” and “aggregateNet” functions were adopted to infer the cellular communication network; (3) “netVisual_aggregate,” “netVisual_signalingRole,” and “netVisual_bubble” were adopted to visualize crosstalk among cells.
文章地址：https://doi.org/10.1016/j.ebiom.2021.103459