【文献解读】PNAS|Specific recognition of two MAX effectors by integrated HMA domains in plant immune re...

背景：

blast fungus M. oryzae ：稻瘟

AVR1-CO39 and AVR-PikD：Thestructurally conserved but sequence-unrelated MAX (Magnaporthe oryzaeavirulence and ToxB-like) effectors

AVR1-CO39 and AVR-PikD：ricenucleotide-binding domain and leucine-rich repeat proteins(NLRs)

HMA：heavymetal-associated (HMA) integrated domain

NLR：a centralnucleotide-binding (NB-ARC) and a C-terminal leucine-rich repeat (LRR) domain

integrated domains (IDs)

结果：

1. crystal structures---- structural andfunctional analysis of a complex between a fungal effector

and an integrated decoy domain (ID) from arice NLR

日积月累：

Decoy   ['diːkɒɪ]  n.诱饵；诱骗 vt. 诱骗 vi. 被诱

Equilibrium    [,ikwɪ'lɪbrɪəm]   n.均衡；平静；保持平衡的能力

dissociation constant (Kd):  离解常数(Kd)

1.Decoys are thought tostem fromthe duplication of virulence target genesand to have lost their original cellular function to only serve as effectortraps.