TCGA中吸烟史定义

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  • Lifelong Non-smoker (less than 100 cigarettes smoked in Lifetime) = 1:从未吸烟
  • Current smoker (includes daily smokers and non-daily smokers or occasional smokers) = 2:当前吸烟(包括规律吸烟者和偶尔吸烟者)
  • Current reformed smoker for > 15 years (greater than 15 years) = 3:戒烟>15年
  • Current reformed smoker for ≤15 years (less than or equal to 15 years) = 4:戒烟<15年
  • Current reformed smoker, duration not specified = 5:戒烟,戒烟时间不详
  • Smoker at Diagnosis = 6:确诊时吸烟
  • Smoking History not documented = 7:不详

这个吸烟史无法从index的临床信息拿到,只能从patient下获取:

cli.query <- GDCquery(project =c("TCGA-LUAD","TCGA-LUSC"),
                  file.type = "xml",
                  data.category = "Clinical") 
GDCdownload(cli.query)
cli <- GDCprepare_clinic(cli.query, clinical.info = "patient")
save(cli,file="./rdata/cli.rda")
cli$tobacco_smoking_history

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