Quinagolide hydrochloride

"目录号: HY-13736A

GPCR/G ProteinNeuronal Signaling-

Quinagolide盐酸盐是一种选择性多巴胺D2受体激动剂, 还是一个促乳素抑制剂.

Dopamine Receptor

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生物活性

Description

Quinagolide hydrochloride is a selective dopamine D2 receptor agonist, also is a prolactin inhibitor. Target: dopamine D2 receptor, prolactinQuinagolide is a selective, D2 receptor agonist (or prolactin-release inhibitor) that is used for the treatment of elevated levels of prolactin. Quinagolide is helpful in reducing prolactin levels to reduce milk production for certain medical reasons and to treat some types of infertility, breast problems and menstrual disorders. Quinagolide exerts a strong and specific inhibitory effect on prolactin release by acting directly on the prolactin-secreting cells of the anterior pituitary without reducing the levels of other pituitary hormones.

Clinical Trial

NCT00329693

Ferring Pharmaceuticals

Ovarian Hyperstimulation Syndrome

June 2006

Phase 2

NCT00665041

Instituto Valenciano de Infertilidad, IVI VALENCIA

Ovarian Hyperstimulation Syndrome

May 2008

Phase 2

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References

[1].Mostafa AA, et al. Spectrophotometric determination of clobetasol propionate, halobetasol propionate, quinagolide hydrochloride, through charge transfer complexation. J Pharm Biomed Anal. 2002 Mar 1;27(6):889-899.