基因组坐标 “0-base” 和 “1-base”

• 讲的特别详细就搬运过来了，搬运链接：The UCSC Genome Browser Coordinate Counting Systems

“1-start, fully-closed” = coordinates positioned within the web-based UCSC Genome Browser. 
“0-start, half-open” = coordinates stored in database tables.

Table 1. UCSC Genome Browser coordinate systems summary

0-start, half-open (0-based)	1-start, fully-closed (1-based)
“BED” format (Browser Extensible Data):	“Position” format:
chr1 127140000 127140001	chr1:127140001-127140001
Note: Spaces, not punctuation	note: Punctuation used, no spaces
When using BED format, brows er & utilities	When using “position” format, browser & utilities
assume coords are 0-start, half-open.	assume coords are 1-start, fully-closed.
Stored in UCSC Genome Browser tables	Positioned in UCSC Genome Browser web interface
To convert to 1-start, fully-closed:	To convert to 0-start, half-open:
add 1 to start, end = same	subtract 1 from start, end = same