bioconductor

名词：

• gene model (e.g., exon, intron, splice site, etc.)

predicts whether an amino acid substitution affects protein function

• SIFT
• PolyPhen

函数

mcols() 把 GRanges 转换为 DataFrame

> class(all)
[1] "GRanges"
attr(,"package")
[1] "GenomicRanges"
> class(mcols(all))
[1] "DataFrame"
attr(,"package")
[1] "S4Vectors"