Enzo丨艾美捷Enzo Ciglitazone解决方案

艾美捷Enzo Ciglitazone是一种噻唑烷二酮类降血糖药。它在遗传性肥胖的C57 Bl/6 ob/ob小鼠中显示抗高血糖活性，并且是选择性PPARγ激动剂（EC50＝3µM）。抑制人间充质干细胞中HUVEC分化和血管生成，并刺激脂肪生成和减少成骨细胞生成。

艾美捷Enzo Ciglitazone基本参数：

配方：C18H23NO3S

兆瓦：333.5

CAS:74772-77-3

RTECS:XJ5813700

纯度：≥98%（高效液相色谱）

鉴定：通过NMR测定。

外观：白色至灰白色。

溶解度：可溶于DMSO（>25mg/ml）或100%乙醇（>25mg/ml）。

运输：环境

长期储存：环境

用途/稳定性：储备溶液在-20°C下储存时可稳定3个月。

RUO-仅供研究使用

艾美捷Enzo Ciglitazone文献参考：

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The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones: T.M. Willson, et al.; J. Med. Chem. 39, 665 (1996), Abstract;

[[omega-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents: B.C. Cantello, et al.; J. Med. Chem. 37, 3977 (1994), Abstract;