Enzo丨艾美捷Enzo N-油基乙醇胺解决方案

艾美捷Enzo N-油基乙醇胺：激活TRPV1。内源性anandamide样脂质，调节食欲，但不与大麻素受体结合。在大鼠中，口服油乙醇胺可抑制食物摄取。通过激活PPARα。抑制神经酰胺酶。

艾美捷Enzo N-油基乙醇胺基本参数：

配方：C20H39NO2

兆瓦：325.5

CAS:111-58-0

纯度：≥98%（薄层色谱）

外观：白色固体。

溶解度：可溶于DMSO（>25mg/ml）、甲醇或100%乙醇（>25mg/ml）。

运输：环境

长期储存：-20°C

搬运：防止光线照射。

RUO-仅供研究使用

 

艾美捷Enzo N-油基乙醇胺文献参考：

Food intake is inhibited by oral oleoylethanolamide: M.J. Nielsen, et al.; J. Lipid Res. 45, 1027 (2004), Abstract;

Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha): M. Guzman, et al.; J. Biol. Chem. 279, 27849 (2004), Abstract;

Activation of TRPV1 by the satiety factor oleoylethanolamide: G.P. Ahern; J. Biol. Chem. 278, 30429 (2003), Abstract;

Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha: J. Fu, et al.; Nature 425, 90 (2003), Abstract;

A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding: R. Gomez, et al.; J. Neurosci. 22, 9612 (2002), Abstract;

An anorexic lipid mediator regulated by feeding: F. Rodriguez de Fonseca, et al.; Nature 414, 209 (2001), Abstract;

Anti-immunoglobulin-induced apoptosis in WEHI 231 cells involves the slow formation of ceramide from sphingomyelin and is blocked by bcl-XL: D.A. Wiesner, et al.; J. Biol. Chem. 272, 9868 (1997), Abstract;

Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides: J. Barg, et al.; Eur. J. Pharmacol. 287, 145 (1995), Abstract;

Differential regulation of sphingomyelinase and ceramidase activities by growth factors and cytokines. Implications for cellular proliferation and differentiation: E. Coroneos, et al.; J. Biol. Chem. 270, 23305 (1995), Abstract;

Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor:: L. Hanus, et al.; J. Med. Chem. 36, 3032 (1993), Abstract;