Avermectin B1

"目录号: HY-15311

Anti-infectionAutophagy-

Avermectin B1 (Abamectin)是驱虫杀虫剂。

ParasiteAutophagy

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生物活性

Description

Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic. IC50 Value: N/ATarget: AntiparasiticAvermectin B1 is a mixture of avermectins containing more than 80% avermectin B1a and less than 20% avermectin B1b. These two components, B1a and B1b have very similar biological and toxicological properties. The avermectins are insecticidal and antihelmintic compounds derived from various laboratory broths fermented by the soil bacterium Streptomyces avermitilis. Avermectin B1 is a natural fermentation product of this bacterium.

Clinical Trial

NCT02533336

National Institute for Medical Research, Tanzania-Kilimanjaro Christian Medical Centre, Tanzania-London School of Hygiene and Tropical Medicine-Centers for Disease Control and Prevention-Brandeis University-United States Agency for International Development (USAID)

Malaria

November 9, 2015

Phase 3

NCT02533336

National Institute for Medical Research, Tanzania-Kilimanjaro Christian Medical Centre, Tanzania-London School of Hygiene and Tropical Medicine-Centers for Disease Control and Prevention-Brandeis University-United States Agency for International Development (USAID)

Malaria

November 9, 2015

Phase 3

NCT02533336

National Institute for Medical Research, Tanzania-Kilimanjaro Christian Medical Centre, Tanzania-London School of Hygiene and Tropical Medicine-Centers for Disease Control and Prevention-Brandeis University-United States Agency for International Development (USAID)

Malaria

November 9, 2015

Phase 3

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References

[1].Mogg TD, Pollitt CC, Willmore JP, Thompson H.Efficacy of avermectin B1 given orally against equine intestinal strongyles and Onchocera microfilaria.Aust Vet J. 1990 Nov;67(11):399-401.

[2].De Chaneet GC, Casey R, Dixon FF, Besier RB, Mitchell RK.Effect of avermectin B1 and benzimidazole anthelmintics on worm egg output of treated cattle.Aust Vet J. 1988 Mar;65(3):85-6.

[3].Seaman JT, Eagleson JS, Carrigan MJ, Webb RF.Avermectin B1 toxicity in a herd of Murray Grey cattle.Aust Vet J. 1987 Sep;64(9):284-5.

[4].Murty US, Jyothi KN, Jamil K.Effect of avermectin B1 (L-676) a metabolite from Streptomyces avermilitis on immatures of Culex quinquefasciatus.Indian J Med Res. 1987 May;85:539-41.

[5].Parrish MD, Roberts RB.Toxicity of avermectin B1 to larval yellowjackets, Vespula maculifrons (Hymenoptera: Vespidae).J Econ Entomol. 1984 Jun;77(3):769-72.