2017-Cell-mTOR Signaling in Growth, Metabolism, and Disease
Figure1.mTORC1andmTORC2(A)ThemTORC1andmTORC2signalingpathways.(B)mTORC1subunitsandrespectivebindingsitesonmTOR.The5.9-A°cryo-EMstructureofmTORC1incomplexwiththeFKBP12-rapamycincomplex(withoutDEPTORand